Article

Antibody Dependent Enhancement (ADE) of Infection into Macrophages Validates the Importance of HERV-K102 Particle Production for Pandemic Preparedness

2024-08-20

Abstract excerpt

Historically, macrophages have been long implicated in the control of the severity of infectious diseases. This has been based on the observations of a higher risk of severe disease and death upon rechallenge with viral variants due to antibody dependent enhance-ment (ADE) of infection into macrophages. The question remains as to what can account for this potent heterologous protection in macrophages? Here it is a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 336b85a6-18e8-5b99-8339-e4c30f96f5af
DOI: 10.20944/preprints202312.0185.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antibody Dependent Enhancement (ADE) of Infection into Macrophages Validates the Importance of HERV-K102 Particle Production for Pandemic PreparednessDOI 10.20944/preprints202312.0185.v2Read

Clues to finding correlates of risk/protection for HIV-1 vaccinesSemantic proximity Read

Conventional and antibody-enhanced DENV infection of human macrophages induces differential immunotranscriptomic profilesSemantic proximity Read

Antibody-dependent DENV infection induces distinct transcriptomic responses in infected and bystander human macrophagesSemantic proximity Read

Anatomy of a Discovery: M1 and M2 MacrophagesSemantic proximity Read

Antibody-dependent enhancement of coronavirusesSemantic proximity Read

Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cellsSemantic proximity Read

Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagySemantic proximity Read

Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection KineticsSemantic proximity Read

Rabies virus uniquely reprograms the transcriptome of human monocyte-derived macrophagesSemantic proximity Read

GM-CSF and M-CSF Driven Differentiation Differentially Regulates Chikungunya Virus Infection and Antiviral Responses in Human Monocyte-Derived MacrophagesSemantic proximity Read

The Lipolysis-Stimulated Lipoprotein Receptor Contributes to Direct and Antibody-Enhanced SARS-CoV-2 PathogenicitySemantic proximity Read