Article

The evolution of genomic, transcriptomic, and single-cell protein markers of metastatic upper tract urothelial carcinoma

2021-11-19

Abstract excerpt

The molecular characteristics of metastatic upper tract urothelial carcinoma (UTUC) are unknown. The genomic and transcriptomic differences between primary and metastatic UTUC is not well described either. We combined whole-exome sequencing, RNA-sequencing, and Imaging Mass Cytometry ™ (IMC ™ ) of 44 tumor samples from 28 patients with high-grade primary and metastatic UTUC. IMC enables spatially resolved single...

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Literature Corpus work: 334659a4-629b-538a-8e75-cb5fcda17983
DOI: 10.1101/2021.11.16.468622

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