Article
Molecular classification and diagnostics of upper urinary tract urothelial carcinoma.
Cancer cell - 14 Jun 2021
Fujii Yoichi, Sato Yusuke, Suzuki Hiromichi, Kakiuchi Nobuyuki, Yoshizato Tetsuichi, Lenis Andrew T, Maekawa Shigekatsu, Yokoyama Akira, Takeuchi Yasuhide, Inoue Yoshikage, Ochi Yotaro, Shiozawa Yusuke, Aoki Kosuke, Yoshida Kenichi, Kataoka Keisuke, Nakagawa Masahiro M, Nannya Yasuhito, Makishima Hideki, Miyakawa Jimpei, Kawai Taketo, Morikawa Teppei, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Nagae Genta, Sanada Masashi, Sugihara Eiji, Sato Taka-Aki, Nakagawa Tohru, Fukayama Masashi, Ushiku Tetsuo, Aburatani Hiroyuki, Miyano Satoru, Coleman Jonathan A, Homma Yukio, Solit David B, Kume Haruki, Ogawa Seishi
Abstract excerpt
Upper urinary tract urothelial carcinoma (UTUC) is one of the common urothelial cancers. Its molecular pathogenesis, however, is poorly understood, with no useful biomarkers available for accurate diagnosis and molecular classification. Through an integrated genetic study involving 199 UTUC samples, we delineate the landscape of genetic alterations in UTUC enabling genetic/molecular classification. According to...
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