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Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma

24 Jan 2022

Abstract excerpt

Recent molecular characterization of primary urothelial carcinoma (UC) may guide future clinical decision-making. For metastatic UC (mUC), a comprehensive molecular characterization is still lacking. We analyzed whole-genome DNA and RNA sequencing data for fresh-frozen metastatic tumor biopsies from 116 mUC patients who were scheduled for palliative systemic treatment within the context of a clinical trial...

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Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Urinary and Genital Oncology Studies

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PMID: 35086719
DOI: 10.1016/j.eururo.2022.01.026

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