Article

Benchmarking long-read genome sequence alignment tools for human genomics applications

2021-07-11

Abstract excerpt

<h4>Background</h4> The utility of long-read genome sequencing platforms has been shown in many fields including whole genome assembly, metagenomics, and amplicon sequencing. Less clear is the applicability of long reads to reference-guided human genomics, the foundation of genomic medicine. Here, we benchmark available platform-agnostic alignment tools on datasets from nanopore and single-molecule real-time plat...

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Literature Corpus work: 98d6ed7e-dbb5-5be5-bc7e-3a6b31aff2a4
DOI: 10.1101/2021.07.09.451840

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