Article

Towards a structural understanding of the mechanism of action of dimeric HCV inhibitors

2014-01-01

Abstract excerpt

Hepatitis C Virus (HCV) is expected to be an increasing global healthcare burden. HCV Infection can progress to major chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). No protective vaccine currently exists against hepatitis C and current therapies are ineffective. NS5A is an essential component of the HCV with roles in RNA replication, modulation of the host cell and assembly of viral particl...

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Literature Corpus work: 3317eedb-bbfd-5855-8e0a-6f9cb437d1b4
DOI: 10.25560/24130

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