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Estimating somatic mutation rates by Duplex Sequencing in non-model organisms: <i>Daphnia magna</i> as a case study

2022-06-01

Abstract excerpt

Somatic mutations are evolutionarily important as determinants of individual organismal fitness, as well as being a focus of clinical research on age-related disease, such as cancer. Identifying somatic mutations and quantifying mutation rates, however, is extremely challenging and genome-wide somatic mutation rates have only been reported for a few model organisms. Here, we describe the application of Duplex Sequ...

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Literature Corpus work
330fe401-77c8-5329-9b34-8eed9fb8d344
DOI
10.1101/2022.05.31.494242
Open publication

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Estimating somatic mutation rates by Duplex Sequencing in non-model organisms: <i>Daphnia magna</i> as a case studyDOI 10.1101/2022.05.31.494242
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