Article

<i>µ</i> Seq: Universal mutation rate quantification via deep sequencing of a single clonal expansion

2025-04-22

Abstract excerpt

Understanding and quantifying mutational processes is fundamental for studying evolution in both clinical and experimental contexts. However, current methods are labor intensive and often lack robustness, particularly in mammalian cells. For example, current approaches that rely on subclonal mutations derived directly from patient samples often result in inconsistent or biased outcomes, leading to potentially unre...

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Literature Corpus work: 2cc7f721-c099-59bb-9318-04dd0d8d7543
DOI: 10.1101/2025.04.17.649315

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