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Article

Emerging proteomic biomarkers of X-linked muscular dystrophy

30 Jul 2019

Abstract excerpt

Introduction: Progressive skeletal muscle wasting is the manifesting symptom of Duchenne muscular dystrophy, an X-linked inherited disorder triggered by primary abnormalities in the DMD gene. The almost complete loss of dystrophin isoform Dp427 causes a multi-system pathology that features in addition to skeletal muscle weakness also late-onset cardio-respiratory deficiencies, impaired metabolism and...

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PMID: 31359811
DOI: 10.1080/14737159.2019.1648214

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