Article

Transcriptomic analysis of mdx mouse muscles reveals a signature of early human Duchenne muscular dystrophy

2021-07-16

Abstract excerpt

<h4>ABSTRACT</h4> The mdx mouse (C57BL/10ScSn- DMD mdx /J) is the oldest model of Duchenne muscular dystrophy (DMD). Mdx remains popular and has not been replaced by newer mouse models, despite criticisms that mdx has a nearly normal lifespan and mild pathology while DMD remains a severe, fatal disease. At some point we noticed that the absence of mdx RNA-seq data limited our ability to assess the results o...

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Literature Corpus work: 85b396c7-8a8e-5ea1-9442-2516c7651969
DOI: 10.1101/2021.07.16.452553

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