Article

Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy

2019-03-26

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease characterized by extensive muscle weakness. Patients with DMD lack a functional dystrophin protein, which transmits force and organizes the cytoskeleton of skeletal muscle. Multiomic studies evaluate combined changes in the transcriptome, proteome, and metabolome, and have been proposed as a way to obtain novel insight about disease processes...

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Literature Corpus work: 141e59dd-9c1e-5acc-877d-66caca51e896
DOI: 10.1101/589424

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