Article

Mitochondria-centered metabolomic map of inclusion body myositis: sex-specific alterations in central carbon metabolism

2024-09-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Inclusion body myositis (IBM) is a disease of aging characterized by progressive muscle loss. Despite its positioning at the intersection of aging, mitochondrial dysfunction and chronic inflammation, limited studies have evaluated the underlying metabolic disturbances in IBM. <h4>Objective</h4> To investigate the mitochondria-centered metabolomic map of IBM in muscle tissue...

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Literature Corpus work: db7d1e88-e2fd-5f4d-baef-35c613762046
DOI: 10.1101/2024.09.29.615665

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