Article

Why does the zebrafish <i>cloche</i> mutant develop lens cataract?

2019-01-15

Abstract excerpt

The zebrafish has become a valuable model for examining ocular lens development, physiology and disease. The zebrafish cloche mutant, first described for its loss of hematopoiesis, also shows reduced eye and lens size, interruption in lens cell differentiation and a cataract likely caused by abnormal protein aggregation. To facilitate the use of the cloche mutant for studies on cataract development and preventio...

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Literature Corpus work: 32bde538-3396-58bb-b2c2-891f663eb452
DOI: 10.1101/521526

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