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Article

Why does the zebrafish cloche mutant develop lens cataract?

PloS one - 1 Jan 2019

Posner Mason, McDonald Matthew S, Murray Kelly L, Kiss Andor J

Abstract excerpt

The zebrafish has become a valuable model for examining ocular lens development, physiology and disease. The zebrafish cloche mutant, first described for its loss of hematopoiesis, also shows reduced eye and lens size, interruption in lens cell differentiation and a cataract likely caused by abnormal protein aggregation. To facilitate the use of the cloche mutant for studies on cataract development and prevention...

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Identifiers

PMID: 30861003
DOI: 10.1371/journal.pone.0211399
PMCID: PMC6413905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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