Article

Effects of α-crystallin gene knockout on zebrafish lens development

2021-12-23

Abstract excerpt

The α-crystallin small heat shock proteins contribute to the transparency and refractive properties of the vertebrate eye lens and prevent the protein aggregation that would otherwise produce lens cataracts, the leading cause of human blindness. There are conflicting data in the literature as to what role the α-crystallins may play in early lens development. In this study, we used CRISPR gene editing to produce ze...

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Literature Corpus work: 150e6a0d-1e3b-5ab7-9bc4-9d36da14b9ff
DOI: 10.1101/2021.12.22.473921

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