Article
Comparison of baseline cataract rates in AB and TL wildtype zebrafish strains.
Experimental eye research - 1 Jun 2024
Khatiwada Bibek, Jones Johanna L, Zhao Duran, Gasperini Robert J, McComish Bennet J, Burdon Kathryn P
Abstract excerpt
Zebrafish are an outstanding model for assessing the involvement of genes in paediatric cataracts. Gene discovery for cataracts is enhanced by manipulation of the genome of zebrafish embryos and comparing the phenotypes of mutant progeny with the wildtype embryos. However, wildtype laboratory fish can also develop cataracts, potentially confounding the results. In this study, we compared the baseline cataract...
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