Article
Arrested differentiation and epithelial cell degeneration in zebrafish lens mutants.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2001
Vihtelic T S, Yamamoto Y, Sweeney M T, Jeffery W R, Hyde D R
Abstract excerpt
In a chemical mutagenesis screen, we identified two zebrafish mutants that possessed small pupils. Genetic complementation revealed these two lines are due to mutations in different genes. The phenotypes of the two mutants were characterized using histologic, immunohistochemical, and tissue transplantation techniques. The arrested lens (arl) mutant exhibits a small eye and pupil phenotype at 48 hr...
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