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IL-21, inflammatory cytokines and hyper polarized CD8<sup>+</sup>T cells are central players in Lupus immune pathology

2022-10-20

Abstract excerpt

Systemic Lupus Erythematous (SLE) is a chronic autoimmune disorder, broadly characterized by systemic inflammation along with heterogeneous clinical manifestations, severe morbidity, moribund organ failure and eventual mortality. In our study, SLE patients displayed higher percentage of activated, inflamed and hyper polarized CD8 + T cells, dysregulated CD8 + T cell differentiation, significantly elevated serum in...

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Literature Corpus work
32988aae-bba2-58f0-94fd-3dd43c489941
DOI
10.1101/2022.10.18.22281177
Open publication

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