Article

Computational identification and experimental characterization of preferred downstream positions in human core promoters

2021-02-02

Abstract excerpt

Metazoan core promoters, which direct the initiation of transcription by RNA polymerase II (Pol II), may contain short sequence motifs termed core promoter elements/motifs ( e.g. the TATA box, initiator (Inr) and downstream core promoter element (DPE)), which recruit Pol II via the general transcription machinery. The DPE was discovered and extensively characterized in Drosophila , where it is strictly dependent...

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Literature Corpus work: 32891904-35fb-557d-855d-20e57ed40d23
DOI: 10.1101/2021.02.02.429413

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