Article

Characteristics of functional enrichment and gene expression level of human putative transcriptional target genes

2016-11-04

Abstract excerpt

<h4>Background</h4> Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional enrichments are still unclear. To address these issues, I predicted human transcriptional target genes using open chromatin regions, ChIP-seq data and DNA binding sequences of transcription factors in databases, and examined functional enrich...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ddce4d46-0e74-5c28-a0b9-c3f8d6c84750
DOI: 10.1101/085654

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characteristics of functional enrichment and gene expression level of human putative transcriptional target genesDOI 10.1101/085654Read

Atlas of Regulated Target Genes of Transcription Factors (ART-TF) in Human ES CellsSemantic proximity Read

Human transcriptional gene regulatory network compiled from 14 data resourcesSemantic proximity Read

A Systematic Study of Motif Pairs That May Facilitate Enhancer-Promoter InteractionsSemantic proximity Read

Discovery of directional chromatin-associated regulatory motifs affecting human gene transcriptionSemantic proximity Read

hTFtarget: a comprehensive database for regulations of human transcription factors and their targetsSemantic proximity Read

Systematic target function annotation of human transcription factors.Semantic proximity Read

Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory dataSemantic proximity Read

Benchmark and integration of resources for the estimation of human transcription factor activitiesSemantic proximity Read

Inference of phenotype-relevant transcriptional regulatory networks elucidates cancer type-specific regulatory mechanisms in a pan-cancer studySemantic proximity Read

Inferring functions of coding and non-coding genes using epigenomic patterns and deciphering the effect of combinatorics of transcription factors binding at promotersSemantic proximity Read

Decoding transcriptional regulation via a human gene expression predictorSemantic proximity Read

Large-scale mapping and systematic mutagenesis of human transcriptional effector domainsSemantic proximity Read