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Trends in DNA Methylation with Age Replicate Across Diverse Human Populations.

Genetics - 1 Jul 2017

Gopalan Shyamalika, Carja Oana, Fagny Maud, Patin Etienne, Myrick Justin W, McEwen Lisa M, Mah Sarah M, Kobor Michael S, Froment Alain, Feldman Marcus W, Quintana-Murci Lluis, Henn Brenna M

Abstract excerpt

Aging is associated with widespread changes in genome-wide patterns of DNA methylation. Thousands of CpG sites whose tissue-specific methylation levels are strongly correlated with chronological age have been previously identified. However, the majority of these studies have focused primarily on cosmopolitan populations living in the developed world; it is not known if age-related patterns of DNA methylation at...

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PMID: 28533441
DOI: 10.1534/genetics.116.195594
PMCID: PMC5500158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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