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The applicability of DNA methylation-based tools in a low-income, sub-Saharan African population: Malawi longitudinal study of families and health

1 Aug 2026

Abstract excerpt

DNA methylation (DNAm)-based tools are predominantly developed in European ancestry, high-income populations, raising questions on their applicability in diverse and rural settings. To evaluate these tools in a sub-Saharan African low-income context, we analyzed genome-wide DNAm data from 49 dried blood spot samples from adults aged 45+ years in the Malawi Longitudinal Study of Families and Health (MLSFH)....

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PMID: 42621248
DOI: 10.1016/j.isci.2026.117104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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