Article

Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth

2020-01-11

Abstract excerpt

Tumors are comprised of cancer cells and a network of non-cancerous stromal cells. Cancer-associated fibroblasts (CAFs) are well known to support tumorigenesis and are emerging as immune modulators. While many leukocyte populations are well studied in cancer, neutrophils have received less attention. Neutrophils can release histone-bound nuclear DNA and cytotoxic granules as extracellular traps (NETs) in a process...

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Literature Corpus work: 320b5d50-19ac-5dc4-a510-f270cc069590
DOI: 10.1101/2020.01.10.901686

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