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Article

NETosis as an oncologic therapeutic target: a mini review

18 Apr 2023

Abstract excerpt

Neutrophil Extracellular Traps (NETs) are a key form of pro-inflammatory cell death of neutrophils characterized by the extrusion of extracellular webs of DNA containing bactericidal killing enzymes. NETosis is heavily implicated as a key driver of host damage in autoimmune diseases where injurious release of proinflammatory enzymes damage surrounding tissue and releases 70 known autoantigens. Recent evidence...

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Identifiers

PMID: 37143649
DOI: 10.3389/fimmu.2023.1170603

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