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Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours

2024-11-18

Abstract excerpt

Tumour associated neutrophils (TANs) can promote metastasis through the interaction of Neutrophil Extracellular Traps (NETs) with tumour cells. Here, we examined the contribution of NETs in the progression of Pancreatic Ductal Adenocarcinoma (PDAC), which is characterized by high metastatic propensity. We carried out consensus clustering and pathway enrichment analysis of NET-related genes in an integrated cohort...

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Literature Corpus work
bb561f8e-eac2-5031-a96e-82384f1f61c2
DOI
10.1101/2024.11.15.622336
Open publication

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Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumoursDOI 10.1101/2024.11.15.622336
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