Article

Regulation of Cell-Type-Specific Transcriptomes by miRNA Networks During Human Brain Development

2018-09-09

Abstract excerpt

MicroRNAs (miRNAs) regulate many cellular events by regulating hundreds of mRNA transcripts. However, it is unclear how miRNA-mRNA interactions are contextualized into the framework of transcriptional heterogeneity among closely related cells of the developing human brain. By combining the multiple complementary approaches, AGO2-HITS-CLIP, single-cell profiling and bipartite network analysis, we show that the miR...

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Literature Corpus work: 32061b80-a902-5a13-b507-f5d0b4d8a01a
DOI: 10.1101/412510

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