Article
Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment.
The EMBO journal - 11 Dec 2013
Aprea Julieta, Prenninger Silvia, Dori Martina, Ghosh Tanay, Monasor Laura Sebastian, Wessendorf Elke, Zocher Sara, Massalini Simone, Alexopoulou Dimitra, Lesche Mathias, Dahl Andreas, Groszer Matthias, Hiller Michael, Calegari Federico
Abstract excerpt
Transcriptome analysis of somatic stem cells and their progeny is fundamental to identify new factors controlling proliferation versus differentiation during tissue formation. Here, we generated a combinatorial, fluorescent reporter mouse line to isolate proliferating neural stem cells, differentiating progenitors and newborn neurons that coexist as intermingled cell populations during brain development....
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