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Key factors underpinning neuroimmune-metabolic-oxidative (NIMETOX) major depression in outpatients: paraoxonase 1 activity, reverse cholesterol transport, increased atherogenicity, protein oxidation, and differently expressed cytokine networks

2025-03-03

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) is associated with neuro-immune – metabolic – oxidative (NIMETOX) pathways. <h4>Aims</h4> To examine the connections among NIMETOX pathways in outpatient MDD (OMDD) with and without metabolic syndrome (MetS); and to determine the prevalence of NIMETOX aberrations in a cohort of OMDD patients. <h4>Methods</h4> We included 67 healthy controls and 66 OMDD patient...

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Literature Corpus work
4650883d-a759-57f2-beee-1fd37872f0a6
DOI
10.1101/2025.03.02.25323183
Open publication

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Key factors underpinning neuroimmune-metabolic-oxidative (NIMETOX) major depression in outpatients: paraoxonase 1 activity, reverse cholesterol transport, increased atherogenicity, protein oxidation, and differently expressed cytokine networksDOI 10.1101/2025.03.02.25323183
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