Article
Effect of load reduction on the calcification of rat tibial tuberosity: Focus on calcification factors and chondrocyte mechanosensors
2023-09-05
Abstract excerpt
The tibial tuberosity has a superficial patellar tendon-embedded portion and a deep uncalcified cartilage portion. Osgood–Schlatter disease occurs because of suppressed calcification of the tibial tuberosity. The tibial tuberosity calcifies with aging, and load reduction degrades the cartilage matrix and promotes calcification. This suggests that reducing mechanical stimulation of the tibial tuberosity promotes ca...
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Identifiers and source
- Literature Corpus work
- 31da9228-bfc7-51d9-a0e3-db9af36d61db
- DOI
- 10.21203/rs.3.rs-3307698/v1
