Article

A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics

2023-04-21

Abstract excerpt

Hemodynamic loading is known to contribute to the development and progression of pulmonary arterial hypertension (PAH). This loading drives changes in mechanobiological stimuli that affect cellular phenotypes and lead to pulmonary vascular remodeling. Computational models have been used to simulate mechanobiological metrics of interest, such as wall shear stress, at single time points for PAH patients. However, th...

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Literature Corpus work: 31d04046-a896-521a-b469-e3e1d1aa312f
DOI: 10.1101/2023.04.20.537714

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