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Article

Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2014

Allen Roblee P, Schelegle Edward S, Bennett Stephen H

Abstract excerpt

Pulmonary hypertension (PH) is associated with progressive changes in arterial network complexity. An allometric model is derived that integrates diameter branching complexity between pulmonary arterioles of generation n and the main pulmonary artery (MPA) via a power-law exponent (X) in dn = dMPA2(-n/X) and the arterial area ratio β = 2(1-2/X). Our hypothesis is that diverse forms of PH demonstrate early...

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Share to Arterioles
Share to Endothelium, Vascular
Share to Hemodynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Models, Cardiovascular

Share to Pulmonary Artery

Share to Stress, Mechanical

Share to Vascular Remodeling

Source

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Identifiers

PMID: 24858853
DOI: 10.1152/ajpheart.00144.2014
PMCID: PMC4121648

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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