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Article

Mechanisms of neural tube closure and defects

1998-01-01

Abstract excerpt

Neural tube closure (neurulation) is a complex process involving many cell phenomena. Both extrinsic and intrinsic forces are essential to elevate the neural plate into the neural folds and to bring the folds into apposition for closure. Extrinsic forces involve the underlying mesenchyme cells and extracellular matrix, nonneural ectoderm, the gut tube and notochord, and cell surface glycoproteins. Intrinsic forces...

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Literature Corpus work
31cabece-1bdc-52bf-8c13-1901cf2a02a1
DOI
10.1002/(sici)1098-2779(1998)4:4<247::aid-mrdd3>3.0.co;2-p
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