Article
The continuing challenge of understanding, preventing, and treating neural tube defects.
Science (New York, N.Y.) - 1 Mar 2013
Wallingford John B, Niswander Lee A, Shaw Gary M, Finnell Richard H
Abstract excerpt
Human birth defects are a major public health burden: The Center for Disease Control estimates that 1 of every 33 United States newborns presents with a birth defect, and worldwide the estimate approaches 6% of all births. Among the most common and debilitating of human birth defects are those affecting the formation of the neural tube, the precursor to the central nervous system. Neural tube defects (NTDs) arise...
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