Article

ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2

2020-11-13

Abstract excerpt

<h4>ABSTRACT</h4> The human protein-coding gene ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domain, previously C6orf106) is a recently-characterised inhibitor of the transcription regulators p300 and CREB-binding protein (CBP). Here we have utilised RNA-seq to define cellular pathways regulated by ILRUN in the context of severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-...

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Literature Corpus work: 31adc834-3a7f-5671-b561-a72768f3d781
DOI: 10.1101/2020.11.13.381343

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