Article

Mitochondrial bioenergetic signatures differentiate asymptomatic from symptomatic Alzheimer’s disease

2025-11-06

Abstract excerpt

Asymptomatic Alzheimer’s disease (AsymAD) refers to individuals who, despite exhibiting amyloid-β plaques and tau pathology comparable to Alzheimer’s disease (AD), maintain cognitive performance similar to cognitively normal individuals. The resilience mechanism in these AsymAD individual remains understudied. We performed a systematic analysis comparing AsymAD and AD across multiple cohorts (ROSMAP, Banner and Mo...

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Literature Corpus work: 318cf059-e328-54a4-992c-2f4729954477
DOI: 10.1101/2025.11.04.686626

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