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Article

Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease.

Biogerontology - 1 Apr 2016

Grimm Amandine, Friedland Kristina, Eckert Anne

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disease that represents the most common form of dementia among the elderly. Despite the fact that AD was studied for decades, the underlying mechanisms that trigger this neuropathology remain unresolved. Since the onset of cognitive deficits occurs generally within the 6th decade of life, except in rare familial case, advancing age is the greatest known...

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Identifiers

PMID: 26468143
DOI: 10.1007/s10522-015-9618-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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