Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease

28 Jan 2019

Abstract excerpt

Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer's disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood. In order to unveil AD specific mitochondrial dysfunctions, this study adopted a discovery-driven approach with isobaric tag for relative and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to ATP Synthase and ATPases Research
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30691479
DOI: 10.1186/s13041-019-0430-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s diseasePMID 30691479Read ↗

Mitochondrial dysfunction in Alzheimer’s disease - a proteomics perspectiveSemantic proximity Read ↗

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapiesSemantic proximity Read ↗

Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathwaysSemantic proximity Read ↗

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advancesSemantic proximity Read ↗

Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?Semantic proximity Read ↗

Recent Advances of Mitochondrial Alterations in Alzheimer’s Disease: A Perspective of Mitochondrial Basic EventsSemantic proximity Read ↗

Current Advances in Mitochondrial Targeted Interventions in Alzheimer’s DiseaseSemantic proximity Read ↗

Disentangling Mitochondria in Alzheimer’s DiseaseSemantic proximity Read ↗

Critical appraisal on mitochondrial dysfunction in Alzheimer’s diseaseSemantic proximity Read ↗

The role of mitochondrial defects and oxidative stress in Alzheimer’s diseaseSemantic proximity Read ↗

Exploring the Mechanisms and Therapeutic Approaches of Mitochondrial Dysfunction in Alzheimer’s Disease: An Educational Literature ReviewSemantic proximity Read ↗

Alterations in Mitochondrial Quality Control in Alzheimer’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.