Article

NRL- and CRX-guided gene network modulates photoreceptor presynapse size and positioning during retinal development

2019-08-30

Abstract excerpt

Unique morphologies of rod and cone photoreceptor presynaptic terminals permit the formation of synapses onto interneurons during retina development. We integrated multiple “omics” datasets of developing rod and S-cone-like photoreceptors and identified 719 genes that are regulated by NRL and CRX, critical transcriptional regulators of rod differentiation, as candidates for controlling presynapse morphology. In v...

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Literature Corpus work: 318adfb5-25eb-5692-9f05-e9b56b8daa96
DOI: 10.1101/753012

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