Article

Cdhr1a and pcdh15b link photoreceptor outer segments with inner segment calyceal processes revealing a potential mechanism for cone-rod dystrophy

2024-07-26

Abstract excerpt

<h4>ABSTRACT</h4> Cone rod dystrophy (CRD) is a macular degeneration disorder characterized by initial cone cell photoreceptor degeneration and subsequently of rod photoreceptors. Mutations in CDHR1, a photoreceptor specific cadherin have been found to be associated with the incidence of cone-rod dystrophy and recapitulated in mouse CDHR1 knockouts. However, the molecular function of CDHR1 remains unknown. CDHR1...

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Literature Corpus work: c64ae9da-24c8-54c1-8a39-54eb57813b8b
DOI: 10.1101/2024.07.26.605360

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