Article

Suramin action in African trypanosomes involves a RuvB-like DNA helicase

2022-10-19

Abstract excerpt

Suramin is one of the oldest drugs in use today. It is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei rhodesiense and it is also used for surra in camels, caused by Trypanosoma evansi . Yet despite one hundred years of use, suramin’s mode of action is not fully understood. Suramin is a polypharmacologic molecule that inhibits diverse proteins....

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Identifiers and source

Literature Corpus work: 317e5e97-9082-5618-94aa-fcb2bf765cfb
DOI: 10.1101/2022.10.17.512644

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