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Targeting the nucleotide metabolism of Trypanosoma brucei and other trypanosomatids

1 May 2023

Abstract excerpt

African sleeping sickness, Chagas disease, and leishmaniasis are life-threatening diseases that together affect millions of people around the world and are caused by different members of the protozoan family Trypanosomatidae. The most studied member of the family is Trypanosoma brucei, which is spread by tsetse flies and causes African sleeping sickness. Nucleotide metabolism in T. brucei and other...

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PMID: 37156497
DOI: 10.1093/femsre/fuad020

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