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100 years since the publication of the suramin formula

7 Dec 2023

Abstract excerpt

Suramin was the first drug developed using the approach of medicinal chemistry by the German Bayer company in the 1910s for the treatment of human African sleeping sickness caused by the two subspecies Trypanosoma brucei gambiense and Trypanosoma brucei rhodesienese. However, the drug was politically instrumentalized by the German government in the 1920s in an attempt to regain possession of its former African...

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PMID: 38057659
DOI: 10.1007/s00436-023-08027-7

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