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Characterization of adenine phosphoribosyltransferase (APRT) activity in <i>Trypanosoma brucei brucei</i> : Only one of the two isoforms is kinetically active

2021-10-20

Abstract excerpt

Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a Neglected Tropical Disease endemic to 36 African countries, with approximately 70 million people currently at risk for infection. Current therapeutics are suboptimal due to toxicity, adverse side effects, and emerging resistance. Thus, both effective and affordable treatments are urgently needed. The causative agent of HAT is the protozoan...

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Literature Corpus work
ba63eeb5-4dfb-5ee7-b20d-6483af879fee
DOI
10.1101/2021.10.20.465077
Open publication

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Characterization of adenine phosphoribosyltransferase (APRT) activity in <i>Trypanosoma brucei brucei</i> : Only one of the two isoforms is kinetically activeDOI 10.1101/2021.10.20.465077
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