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Analysis of associations between polygenic risk score and COVID-19 severity in a Russian population using low-pass genome sequencing

2023-11-20

Abstract excerpt

<h4>ABSTRACT</h4> The course of COVID-19 is characterized by wide variability, with genetics playing a contributing role. Through large-scale genetic association studies, a significant link between genetic variants and disease severity was established. However, individual genetic variants identified thus far have shown modest effects, indicating a polygenic nature of this trait. To address this, a polygenic risk s...

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Literature Corpus work
31517657-19ae-5934-aded-dfb7ac891fc0
DOI
10.1101/2023.11.20.23298335
Open publication

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Analysis of associations between polygenic risk score and COVID-19 severity in a Russian population using low-pass genome sequencingDOI 10.1101/2023.11.20.23298335
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