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The three YTHDF paralogs and VIRMA are the major tumor drivers among the m <sup>6</sup> A core genes in a pan-cancer analysis

2024-06-13

Abstract excerpt

N 6 -methyladenosine (m 6 A) is the most abundant internal modification in mRNAs. Despite accumulating evidence for the profound impact of m 6 A on cancer biology, there are conflicting reports that alterations in genes encoding the m 6 A machinery proteins can either promote or suppress cancer, even in the same tumor type. Using data from The Cancer Genome Atlas, we performed a pan-cancer investigation of 15...

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Literature Corpus work
2044906f-cd15-59f3-b510-f04ee517c46f
DOI
10.1101/2024.06.13.598899
Open publication

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