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Article

TORC1 integrates metabolic state transitions during aging

2026-05-21

Abstract excerpt

Target of rapamycin complex 1 (TORC1) coordinates nutrient availability with anabolic metabolism, yet how TORC1-linked metabolic states influence cellular aging remains unclear. Using genetic, transcriptomic, metabolomic, and pharmacological analyses in prototrophic Saccharomyces cerevisiae , we identify context-dependent metabolic state transitions that uncouple cellular proliferation from long-term survival dur...

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Identifiers and source

Literature Corpus work
313b6baa-63db-515a-8194-ed344e95f754
DOI
10.64898/2026.05.18.726092
Open publication

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TORC1 integrates metabolic state transitions during agingDOI 10.64898/2026.05.18.726092
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