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Article

Interplay among Gcn5, Sch9 and mitochondria during chronological aging of wine yeast is dependent on growth conditions.

PloS one - 1 Jan 2015

Picazo Cecilia, Orozco Helena, Matallana Emilia, Aranda Agustín

Abstract excerpt

Saccharomyces cerevisiae chronological life span (CLS) is determined by a wide variety of environmental and genetic factors. Nutrient limitation without malnutrition, i.e. dietary restriction, expands CLS through the control of nutrient signaling pathways, of which TOR/Sch9 has proven to be the most relevant, particularly under nitrogen deprivation. The use of prototrophic wine yeast allows a better understanding...

Topics

Autophagy
Cell Nucleus
Endopeptidases
Histone Acetyltransferases
Intracellular Signaling Peptides and Proteins
Longevity
Mitochondria
Nitrogen
Phenotype
Protein Kinases
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae Proteins

Signal Transduction

Transcription Factors

Wine

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Identifiers

PMID: 25658705
DOI: 10.1371/journal.pone.0117267
PMCID: PMC4319768

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