Article

Assessing dose-response relations of lipid traits with coronary artery disease, all-cause mortality, and cause-specific mortality: a linear and non-linear Mendelian randomization study

2023-09-27

Abstract excerpt

<h4>Importance</h4> Apolipoprotein B (apoB), low-density lipoprotein cholesterol (LDL-C), and possibly triglycerides (TG) play causal roles in the aetiology of coronary artery disease (CAD). However, trial evidence for effects of intensive LDL-C lowering and TG lowering on mortality is less definitive. <h4>Objectives</h4> To investigate dose-response relations of apoB, LDL-C, and TG with CAD and mortality overall,...

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Literature Corpus work: 18e28da4-182b-5757-a4a3-7196dd4674c2
DOI: 10.1101/2023.09.27.23296203

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