Article

Innate antiviral readiness drives the expansion of protective T stem cell memory against influenza

2025-12-10

Abstract excerpt

The development of T-cell-based influenza vaccines relies on eliciting broad CD8+ T-cell immunity, wherein T stem cell-like memory (TSCM) cells serve as the ultimate long-lived reservoir for immune memory, thereby unlocking the potential for durable protection against viral drift and shift. However, the specific immunological cues that drive the robust expansion and functional preservation of this self-renewing, m...

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Literature Corpus work: 3105e67a-1e7e-5d3b-b323-61bc70c4f142
DOI: 10.64898/2025.12.06.692757

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