Article

Spatiotemporal development of the human T follicular helper cell response to Influenza vaccination

2023-08-31

Abstract excerpt

We profiled blood and draining lymph node (LN) samples from human volunteers after influenza vaccination over two years to define evolution in the T follicular helper cell (TFH) response. We show LN TFH cells expanded in a clonal-manner during the first two weeks after vaccination and persisted within the LN for up to six months. LN and circulating TFH (cTFH) clonotypes overlapped but had distinct kinetics. LN TFH...

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Identifiers and source

Literature Corpus work: b530dd68-ae86-5a53-b5a2-bc4465421708
DOI: 10.1101/2023.08.29.555186

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